While there’s no cure for psoriasis, a range of treatments can improve visible and uncomfortable symptoms. But it’s an extremely unpredictable disease—what works for one person won’t necessarily work for the next. And treatment often involves trying a few different methods before finding what really works.

The National Psoriasis Foundation recommends doctors set a goal of either reducing a patient’s psoriasis down to covering 1 percent or less of their body surface, or achieving a 75 percent reduction in psoriasis symptoms, within three months of starting the treatment. This is based on the results of a study published in the Journal of the American Academy of Dermatology in 2016. (One percent of body surface equals about the size of the palm of the person’s hand.)

Your personal goal may be the same as this, or it may differ, but the important thing to know is that there are some things you can do to help boost the odds of achieving it.